Science Digest Newsletter - October 2025
View in browser

OCTOBER 2025

PARC Science Digest Logo colours on grey
Cover_October_2025_1_SD

Reusing chemical data across disciplines: initiatives and common challenges

 

Journal
Chemistry International, Vol. 47 (2025), 2, 12-16.

 

Authors

Fatima Mustafa, Iseult Lynch, Jan Theunis, Anjana Elapavalore, Hiba Mohammed Taha, Jeremy Frey, Felix Bach, Christian Bonatto Minella and Leah McEwen

 

Work package
7

Read key messages

Cover_October_2025_2_SD

Spatio-temporal transcriptomic analysis reveals distinct nephrotoxicity, DNA damage, and regeneration response after cisplatin

 

Journal
Cell Biology and Toxicology, Vol. 41 (2025), 49.

 

Authors
Lukas S. Wijaya, Steven J. Kunnen, Panuwat Trairatphisan, Ciarán P. Fisher, Meredith E. Crosby, Kai Schaefer, Karen Bodié, Erin E. Vaughan, Laura Breidenbach, Thomas Reich, Diana Clausznitzer, Sylvestre Bonnet, Sipeng Zheng, Chantal Pont, James L. Stevens, Sylvia E. Le Dévédec, Bob van de Water

 

Work package
5,6

Read key messages

Cover_October_2025_3_SD

The European Partnership PARC’s role in actively promoting the uptake of new approach methodologies and next-generation risk assessment into regulatory risk assessment practice

 

Journal
Current Opinion in Toxicology, Vol. 42 (2025), 100517.

 

Authors
Matthias Herzler, Mirjam Luijten, Philip Marx-Stoelting, Gilles Rivière

 

Work package
2,5,6

Read key messages

Cover_October_2025_4_SD

Machine learning-based prediction of fish acute mortality: implementation, interpretation, and regulatory relevance

 

Journal
Environmental Science: Advances, Vol. 3 (2024), 1124-1138.

 

Authors
Lilian Gasser, Christoph Schür, Fernando Perez-Cruz, Kristin Schirmer, Marco Baity Jesi

 

Work package
5

Read key messages

Cover_October_2025_5_SD

Physiologically based kinetic (PBK) modeling as a new approach methodology (NAM) for predicting systemic levels of gut microbial metabolites

 

Journal
Toxicology Letters, Vol. 396 (2024), 94-102.

 

Authors
Maja Stevanoska, Jacob Folz, Karsten Beekmann, Georg Aichinger Benskin

 

Work package
5

Read key messages

Cover_October_2025_6_SD

The integrated stress response-related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability

 

Journal
Liver International, Vol. 44 (2024), 3, 760-775.

 

Authors
Matthijs Vlasveld, Giulia Callegaro, Ciarán Fisher, Julie Eakins, Paul Walker, Samantha Lok, Siddh van Oost, Brechtje de Jong, Damiano Pellegrino-Coppola, Gerhard Burger, Steven Wink, Bob van de Water

 

Work package
5

Read key messages

Cover_October_2025_7_SD

Making food systems more resilient to food safety risks by including artificial intelligence, big data, and internet of things into food safety early warning and emerging risk identification tools

 

Journal
Comprehensive Reviews in Food Science and Food Safety, Vol. 23 (2024), 1, e13296.

 

Authors
Wenjuan Mu, Gijs A. Kleter, Yamine Bouzembrak, Eleonora Dupouy, Lynn J. Frewer, Fadi Naser Radwan Al Natour, H. J. P. Marvin

 

Work package
8

Read key messages

Cover_October_2025_8_SD

Brain-derived neurotrophic factor (BDNF): an effect biomarker of neurodevelopment in human biomonitoring programs

 

Journal
Frontiers in Toxicology, Vol. 5 (2024), 1319788.

 

Authors
Andrea Rodríguez-Carrillo, Veerle J. Verheyen , Alexander L. N. Van Nuijs, Mariana F. Fernandez, Sylvie Remy

 

Work package
4

Read key messages

More info on eu-parc.eu

List of work packages (WPs)

WP 1 Partnership management and coordination
WP 2 A common science-policy-agenda
WP 3 Synergies, collaborations and awareness
WP 4 Monitoring and exposure
WP 5 Hazard assessment

WP 6 Innovation in regulatory risk assessment
WP 7 FAIR data
WP 8 Concepts and toolboxes
WP 9 Building infrastructural and human capacities

Linkedin-w
Twitter-X-w
Facebook-w
Instagram-w
ENCo-FundedbytheEU

The subscription service is provided by the European Environment Agency.

 

European Environment Agency

eea.europa.eu

 Kongens Nytorv 6, 1050, Copenhagen K, Denmark

 

You receive this email because you subscribed to PARC newsletters. Manage your subscription: PARC Science Digest

Update subscription